FGF acidic (Active) Protéine
Aperçu rapide pour FGF acidic (Active) Protéine (ABIN2468429)
Antigène
Type de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
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Attributs du produit
- Biological activity was determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 is < 0.1 ng/mL, in the presence of 10 μg/mL heparin, corresponding to a specific activity of > 1 x 107 units/mg.
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niveau d'endotoxine
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Conseil sur la manipulation
- As with any protein, exposing FGF-acidic recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Stock
- -20 °C
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Stockage commentaire
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted FGF-acidic stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Date de péremption
- 24 months
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- FGF acidic
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Autre désignation
- FGF-Acidic
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Sujet
- FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant rat FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.
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ID gène
- 25317
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NCBI Accession
- NP_036978
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OMIM
- 6978839
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UniProt
- P61149
Antigène
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