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FGF acidic (Active) Protéine

Cette protéine Recombinant est produite dans Escherichia coli (E. coli).
N° du produit ABIN2468429

Aperçu rapide pour FGF acidic (Active) Protéine (ABIN2468429)

Antigène

FGF acidic

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 2
  • 1
Rat

Source

  • 3
Escherichia coli (E. coli)

Pureté

< 95 % by SDS-PAGE gel and HPLC analyses.
  • Séquence

    MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D

    Attributs du produit

    Biological activity was determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 is < 0.1 ng/mL, in the presence of 10 μg/mL heparin, corresponding to a specific activity of > 1 x 107 units/mg.

    niveau d'endotoxine

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Conseil sur la manipulation

    As with any protein, exposing FGF-acidic recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    Stock

    -20 °C

    Stockage commentaire

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted FGF-acidic stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    Date de péremption

    24 months
  • Antigène

    FGF acidic

    Autre désignation

    FGF-Acidic

    Sujet

    FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant rat FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

    ID gène

    25317

    NCBI Accession

    NP_036978

    OMIM

    6978839

    UniProt

    P61149
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