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GDF7 Protéine

Protéine Recombinant GDF7 exprimée dans Escherichia coli (E. coli).
N° du produit ABIN2468476

Aperçu rapide pour GDF7 Protéine (ABIN2468476)

Antigène

Voir toutes GDF7 Protéines
GDF7 (Growth Differentiation Factor 7 (GDF7))

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 3
  • 2
  • 1
  • 1
Humain

Source

  • 6
  • 1
Escherichia coli (E. coli)

Pureté

< 98 % by SDS-PAGE gel and HPLC analyses.
  • Séquence

    TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR

    Attributs du produit

    Biological activity was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Conseil sur la manipulation

    As with any protein, exposing GDF-7 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    Stock

    -20 °C

    Stockage commentaire

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GDF-7 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    Date de péremption

    24 months
  • Antigène

    GDF7 (Growth Differentiation Factor 7 (GDF7))

    Autre désignation

    GDF-7

    Sujet

    GDF-7 belongs to the TGF-beta superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissue. Recombinant human GDF-7 is a 28 kDa disulfide linked homodimer containing two 129 amino acid residues.

    ID gène

    151449

    NCBI Accession

    NP_878248

    OMIM

    61835232

    UniProt

    Q7Z4P5

    Pathways

    Tube Formation
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