MSTN Protein (Propeptide)

N° du produit ABIN2468877

Cette protéine Recombinant MSTN est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour MSTN Protein (Propeptide) (ABIN2468877)

Antigène: MSTN (Myostatin (MSTN))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: < 98 % by SDS-PAGE gel and HPLC analyses.

Détail du produit

Attributs du protein: Propeptide

Séquence: MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR

Attributs du produit: Biological activity was determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC - 11 cells. The expected ED50is 0.01 - 0.04 μg/mL in the presence of 50 ng/mL Myostatin.

niveau d'endotoxine: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Conseil sur la manipulation: As with any protein, exposing Myostatin Propeptide recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Stock: -20 °C

Stockage commentaire: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Myostatin Propeptide is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Date de péremption: 24 months

Détail du antigène

Antigène: MSTN (Myostatin (MSTN))

Autre désignation: Myostatin

Sujet: Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200 % ) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.

ID gène: 2660

NCBI Accession: NP_005250

OMIM: 4885259

UniProt: O14793