Resistin Protein (RETN)
Aperçu rapide pour Resistin Protein (RETN) (ABIN2469024)
Antigène
Voir toutes Resistin (RETN) ProtéinesType de proteíne
Origine
Source
Pureté
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Séquence
- SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLASCPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL QVAS
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niveau d'endotoxine
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Conseil sur la manipulation
- As with any protein, exposing Resistin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Stock
- -20 °C
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Stockage commentaire
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Resistin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Date de péremption
- 24 months
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- Resistin (RETN)
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Autre désignation
- Resistin
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Sujet
- Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family , Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant murine Resistin is a 20.2 kDa disulfide-linked homodimeric protein composed of two identical 94 amino acid chains linked by a single disulfide bond.
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ID gène
- 57264
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NCBI Accession
- NP_001191888
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OMIM
- 326368221
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UniProt
- Q99P87
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Antigène
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