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Resistin Protein (RETN)

Cette protéine Recombinant Resistin est exprimée dans Escherichia coli (E. coli).
N° du produit ABIN2469024

Aperçu rapide pour Resistin Protein (RETN) (ABIN2469024)

Antigène

Voir toutes Resistin (RETN) Protéines
Resistin (RETN)

Type de proteíne

Recombinant

Origine

  • 19
  • 7
  • 4
  • 3
  • 1
Souris

Source

  • 20
  • 8
  • 1
  • 1
Escherichia coli (E. coli)

Pureté

< 98 % by SDS-PAGE gel and HPLC analyses.
  • Séquence

    SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLASCPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL QVAS

    niveau d'endotoxine

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Conseil sur la manipulation

    As with any protein, exposing Resistin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    Stock

    -20 °C

    Stockage commentaire

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Resistin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    Date de péremption

    24 months
  • Antigène

    Resistin (RETN)

    Autre désignation

    Resistin

    Sujet

    Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family , Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant murine Resistin is a 20.2 kDa disulfide-linked homodimeric protein composed of two identical 94 amino acid chains linked by a single disulfide bond.

    ID gène

    57264

    NCBI Accession

    NP_001191888

    OMIM

    326368221

    UniProt

    Q99P87

    Pathways

    Feeding Behaviour, Smooth Muscle Cell Migration
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