Protein A Protéine

N° du produit ABIN2648105

Protéine Native Protein A exprimée dans Staphylococcus aureus.

Aperçu rapide pour Protein A Protéine (ABIN2648105)

Antigène: Protein A

Type de proteíne: Native

Origine: Staphylococcus aureus

Source: Staphylococcus aureus

Pureté: > 95 % pure

Détail du produit

Attributs du produit: Immunoglobulin-binding bacterial Protein A solution
Protein Source: Staphylococcus aureus

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C.

Détail du antigène

Antigène: Protein A

Sujet: Protein A is a 40-60 kDa MSCRAMM surface protein originally found in the cell wall of the bacteria Staphylococcus aureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two-component system called ArlS-ArlR. It has found use in biochemical research because of its ability to bind immunoglobulins. It binds proteins from many of mammalian species, most notably IgGs. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. The result of this type of interaction is that, in serum, the bacteria will bind IgG molecules in the wrong orientation (in relation to normal antibody function) on their surface which disrupts opsonization and phagocytosis.
Description: Staphylococcus aureus.