Complement C8 Protein (C8) (Myc-DYKDDDDK Tag)
Aperçu rapide pour Complement C8 Protein (C8) (Myc-DYKDDDDK Tag) (ABIN2712454)
Antigène
Type de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette Complement C8 protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human Complement C8 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Complement C8 (C8)
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Autre désignation
- Complement c8
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Sujet
- This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 63.4 kDa
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NCBI Accession
- NP_000057
Antigène
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