KRT8 Protein (Myc-DYKDDDDK Tag)
Aperçu rapide pour KRT8 Protein (Myc-DYKDDDDK Tag) (ABIN2712835)
Antigène
Voir toutes KRT8 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette KRT8 protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human Cytokeratin 8 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- KRT8 (Keratin 8 (KRT8))
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Autre désignation
- Cytokeratin 8
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Sujet
- This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
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Poids moléculaire
- 53.5 kDa
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NCBI Accession
- NP_002264
Antigène
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