Claudin 1 Protein (CLDN1) (Myc-DYKDDDDK Tag)
Aperçu rapide pour Claudin 1 Protein (CLDN1) (Myc-DYKDDDDK Tag) (ABIN2712852)
Antigène
Voir toutes Claudin 1 (CLDN1) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette Claudin 1 protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human Claudin-1 / CLDN1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Claudin 1 (CLDN1)
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Autre désignation
- Claudin-1,cldn1
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Sujet
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
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Poids moléculaire
- 22.6 kDa
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NCBI Accession
- NP_066924
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Antigène
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