CBS Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2713257

Détail du produit

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CBS protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CBS protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Autre désignation: Cbs (CBS Produits)

Synonymes: hip4 Protein, GB12529 Protein, CBS Protein, DDBDRAFT_0189727 Protein, DDBDRAFT_0191292 Protein, DDB_0189727 Protein, DDB_0191292 Protein, cbs Protein, AI047524 Protein, AI303044 Protein, HIP4 Protein, cb442 Protein, wu:fb37g05 Protein, wu:fm61c07 Protein, wu:fq06c06 Protein, zgc:113704 Protein, cystathionine-beta-synthase L homeolog Protein, cystathionine-beta-synthase Protein, cystathionine beta-synthase Protein, cystathionine beta-synthase CBS Protein, cystathionine beta synthase Protein, cystathionine-beta-synthase S homeolog Protein, cystathionine-beta-synthase b Protein, cbs.L Protein, cbs Protein, Cbs Protein, CBS Protein, CNA06170 Protein, Tb11.02.5400 Protein, cysB Protein, LOC100635325 Protein, cbs.S Protein, cbsb Protein

Sujet: The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 60.4 kDa

NCBI Accession: NP_000062