CD1a Protein (CD1a) (Myc-DYKDDDDK Tag)
Aperçu rapide pour CD1a Protein (CD1a) (Myc-DYKDDDDK Tag) (ABIN2713480)
Antigène
Voir toutes CD1a ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette CD1a protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human CD1a protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CD1a
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Autre désignation
- CD1a
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Sujet
- This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 35.2 kDa
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NCBI Accession
- NP_001754
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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