CD2AP Protein (Myc-DYKDDDDK Tag)
Aperçu rapide pour CD2AP Protein (Myc-DYKDDDDK Tag) (ABIN2713486)
Antigène
Voir toutes CD2AP (Cd2ap) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette CD2AP protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human CD2-associated protein protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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CD2-Associated Protein (Cd2ap) (AA 1-637) protein (His tag)
custom-made Cd2ap Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD2-Associated Protein (Cd2ap) (AA 1-639) protein (His tag)custom-made Cd2ap Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD2-Associated Protein (Cd2ap) proteinCd2ap Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
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Autre désignation
- CD2-Associated Protein
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Sujet
- This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
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Poids moléculaire
- 71.3 kDa
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NCBI Accession
- NP_036252
Antigène
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