CD2AP Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2713486

Détail du produit

Antigène: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD2AP protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CD2-associated protein protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Autre désignation: CD2-Associated Protein (Cd2ap Produits)

Synonymes: cd2apl Protein, fj51c01 Protein, im:7153970 Protein, si:ch211-207n9.1 Protein, wu:fj51c01 Protein, zgc:103705 Protein, DKFZp469E061 Protein, CMS Protein, AL024079 Protein, C78928 Protein, METS-1 Protein, Mets1 Protein, CD2-associated protein L homeolog Protein, CD2 associated protein Protein, CD2-associated protein Protein, cd2ap.L Protein, CD2AP Protein, cd2ap Protein, Cd2ap Protein

Sujet: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Poids moléculaire: 71.3 kDa

NCBI Accession: NP_036252