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CD22 Protein (Myc-DYKDDDDK Tag)

Cette protéine Recombinant CD22 est exprimée dans HEK-293 Cells.
N° du produit ABIN2713507

Aperçu rapide pour CD22 Protein (Myc-DYKDDDDK Tag) (ABIN2713507)

Antigène

Voir toutes CD22 Protéines
CD22 (CD22 Molecule (CD22))

Type de proteíne

Recombinant

Origine

  • 25
  • 6
  • 3
  • 1
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  • 1
  • 1
  • 1
Humain

Source

  • 21
  • 6
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  • 3
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  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Pureté

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification/Conjugué

    Cette CD22 protéine est marqué à la Myc-DYKDDDDK Tag.

    Attributs du produit

    • Recombinant human CD22 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Indications d'application

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Commentaires

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Stock

    -80 °C

    Stockage commentaire

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène

    CD22 (CD22 Molecule (CD22))

    Autre désignation

    CD22

    Sujet

    Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. [UniProtKB/Swiss-Prot Function]

    Poids moléculaire

    95.2 kDa

    NCBI Accession

    NP_001762
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