CD22 Protein (Myc-DYKDDDDK Tag)
Aperçu rapide pour CD22 Protein (Myc-DYKDDDDK Tag) (ABIN2713507)
Antigène
Voir toutes CD22 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette CD22 protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human CD22 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CD22 (CD22 Molecule (CD22))
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Autre désignation
- CD22
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Sujet
- Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. [UniProtKB/Swiss-Prot Function]
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Poids moléculaire
- 95.2 kDa
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NCBI Accession
- NP_001762
Antigène
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