F11R Protéine

N° du produit ABIN2713651

Détail du produit

Antigène: F11R (F11 Receptor (F11R))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CD321 / JAM1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: < 0.1 EU per μg protein as determined by LAL test

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 100 mM Glycine, pH 7.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: F11R (F11 Receptor (F11R))

Autre désignation: Cd321,jam1 (F11R Produits)

Synonymes: CD321 Protein, JAM Protein, JAM1 Protein, JAMA Protein, JCAM Protein, KAT Protein, PAM-1 Protein, 9130004G24 Protein, AA638916 Protein, ESTM33 Protein, JAM-1 Protein, JAM-A Protein, Jcam Protein, Jcam1 Protein, Ly106 Protein, Jam1 Protein, F11 receptor Protein, F11R Protein, F11r Protein

Sujet: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5&apos alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Poids moléculaire: 23.9 kDa

NCBI Accession: NP_058642

Pathways: Cell-Cell Junction Organization