Integrin Alpha2b Protein (CD41) (Myc-DYKDDDDK Tag)

N° du produit ABIN2713707

Détail du produit

Antigène: Integrin Alpha2b (CD41)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Integrin Alpha2b protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CD41 / ITGA2B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Integrin Alpha2b (CD41)

Autre désignation: Cd41,itga2b (CD41 Produits)

Synonymes: AI172977 Protein, CD41 Protein, CD41B Protein, GpIIb Protein, alphaIIb Protein, BDPLT16 Protein, BDPLT2 Protein, GP2B Protein, GPIIb Protein, GT Protein, GTA Protein, HPA3 Protein, integrin alpha 2b Protein, integrin subunit alpha 2b Protein, Itga2b Protein, ITGA2B Protein

Sujet: This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.

Poids moléculaire: 110 kDa

NCBI Accession: NP_000410

Pathways: Integrin Complex