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Actl7b Protein (Myc-DYKDDDDK Tag)

Protéine Recombinant Actl7b exprimée dans HEK-293 Cells.
N° du produit ABIN2714372

Aperçu rapide pour Actl7b Protein (Myc-DYKDDDDK Tag) (ABIN2714372)

Antigène

Voir toutes Actl7b Protéines
Actl7b (Actin-Like 7b (Actl7b))

Type de proteíne

Recombinant

Origine

  • 3
  • 2
  • 1
  • 1
  • 1
Humain

Source

  • 3
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Pureté

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification/Conjugué

    Cette Actl7b protéine est marqué à la Myc-DYKDDDDK Tag.

    Attributs du produit

    • Recombinant human ACTL7B protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Indications d'application

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Commentaires

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Stock

    -80 °C

    Stockage commentaire

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène

    Actl7b (Actin-Like 7b (Actl7b))

    Autre désignation

    Actl7b

    Sujet

    The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.

    Poids moléculaire

    45.1 kDa

    NCBI Accession

    NP_006677
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