BMP10 Protéine
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- Antigène Voir toutes BMP10 Protéines
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- HEK-293 Cells
- Application
- Protein Interaction (PI), Standard (STD), Antibody Production (AbP), Functional Studies (Func)
- Specificité
- Optimal preservation of protein structure, post-translational modifications and functions.
- Attributs du produit
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- Recombinant human BMP10 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Pureté
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- niveau d'endotoxine
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 4.0-6.0 ng/ml.
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- Discover our top product BMP10 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Conseil sur la manipulation
- Resuspend the protein in the desired concentration in proper buffer
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- Autre désignation
- Bmp10 (BMP10 Produits)
- Synonymes
- BMP10 Protein, si:dkey-13n15.5 Protein, Bmp10 Protein, BMP9 Protein, BMP-10 Protein, bone morphogenetic protein 10 Protein, BMP10 Protein, bmp10 Protein, LOC662386 Protein, Bmp10 Protein
- Sujet
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation.
- Poids moléculaire
- 24.4 kDa
- NCBI Accession
- NP_055297
- Pathways
- Hormone Activity, Regulation of Muscle Cell Differentiation
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