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DAXX Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

DAXX Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2719322
  • Antigène Voir toutes DAXX Protéines
    DAXX (Death-Domain Associated Protein (DAXX))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 3
    Origine
    • 7
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette DAXX protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Death-domain associated protein (DAXX), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DAXX Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    DAXX (Death-Domain Associated Protein (DAXX))
    Abstract
    DAXX Produits
    Synonymes
    BING2 Protein, DAP6 Protein, EAP1 Protein, LOC100226911 Protein, daxx Protein, si:dz179b20.7 Protein, wu:fd15c03 Protein, death domain associated protein Protein, Fas death domain-associated protein Protein, 28S ribosomal protein S29, mitochondrial Protein, death-domain associated protein Protein, death-associated protein 6 L homeolog Protein, DAXX Protein, Daxx Protein, LOC100226911 Protein, daxx.L Protein, daxx Protein
    Sujet
    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
    Poids moléculaire
    82.7 kDa
    NCBI Accession
    NP_001135442
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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