DAXX Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2719322

Protéine Recombinant DAXX exprimée dans HEK-293 Cells.

Aperçu rapide pour DAXX Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2719322)

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Attributs du protein: Transcript Variant 3

Purification/Conjugué: Cette DAXX protéine est marqué à la Myc-DYKDDDDK Tag.

Attributs du produit:

• Recombinant human Death-domain associated protein (DAXX), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Sujet: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 82.7 kDa

NCBI Accession: NP_001135442

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway