Dystrophin Protein (DMD) (Myc-DYKDDDDK Tag)

N° du produit ABIN2719890

Cette protéine Recombinant Dystrophin est produite dans HEK-293 Cells.

Aperçu rapide pour Dystrophin Protein (DMD) (Myc-DYKDDDDK Tag) (ABIN2719890)

Antigène: Dystrophin (DMD)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Purification/Conjugué: Cette Dystrophin protéine est marqué à la Myc-DYKDDDDK Tag.

Attributs du produit:

• Recombinant human Dystrophin / DMD (transcript variant Dp140b) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Dystrophin (DMD)

Autre désignation: Dystrophin,dmd

Sujet: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.

Poids moléculaire: 143 kDa

NCBI Accession: NP_004012

Pathways: Skeletal Muscle Fiber Development