GFRA2 Protein (Transcript Variant 2)

N° du produit ABIN2721854

Protéine Recombinant GFRA2 exprimée dans HEK-293 Cells.

Aperçu rapide pour GFRA2 Protein (Transcript Variant 2) (ABIN2721854)

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Attributs du protein: Transcript Variant 2

Attributs du produit:

• Recombinant human GFRA2 / GDNFR-beta (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

niveau d'endotoxine: < 0.1 EU per μg protein as determined by LAL test

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Autre désignation: Gfra2,gdnfr-beta

Sujet: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 47.8 kDa

NCBI Accession: NP_001158510