Interleukin enhancer-binding factor 3 (ILF3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)
Aperçu rapide pour Interleukin enhancer-binding factor 3 (ILF3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) (ABIN2723411)
Antigène
Voir toutes Interleukin enhancer-binding factor 3 (ILF3) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- Transcript Variant 1
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Purification/Conjugué
- Myc-DYKDDDDK Tag
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Attributs du produit
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- Recombinant human ILF3 / DRBF (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Interleukin enhancer-binding factor 3 (ILF3)
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Autre désignation
- Ilf3,drbf
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Sujet
- This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014].
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Poids moléculaire
- 95.2 kDa
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NCBI Accession
- NP_036350
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Pathways
- M Phase
Antigène
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