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Interleukin enhancer-binding factor 3 (ILF3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)

Protéine Recombinant exprimée dans HEK-293 Cells.
N° du produit ABIN2723411

Aperçu rapide pour Interleukin enhancer-binding factor 3 (ILF3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) (ABIN2723411)

Antigène

Voir toutes Interleukin enhancer-binding factor 3 (ILF3) Protéines
Interleukin enhancer-binding factor 3 (ILF3)

Type de proteíne

Recombinant

Origine

  • 5
  • 2
Humain

Source

  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Pureté

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Attributs du protein

    Transcript Variant 1

    Purification/Conjugué

    Myc-DYKDDDDK Tag

    Attributs du produit

    • Recombinant human ILF3 / DRBF (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Indications d'application

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Commentaires

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Stock

    -80 °C

    Stockage commentaire

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène

    Interleukin enhancer-binding factor 3 (ILF3)

    Autre désignation

    Ilf3,drbf

    Sujet

    This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014].

    Poids moléculaire

    95.2 kDa

    NCBI Accession

    NP_036350

    Pathways

    M Phase
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