Occludin Protein (OCLN) (Myc-DYKDDDDK Tag)
Aperçu rapide pour Occludin Protein (OCLN) (Myc-DYKDDDDK Tag) (ABIN2727862)
Antigène
Voir toutes Occludin (OCLN) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette Occludin protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human Occludin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Occludin (OCLN)
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Autre désignation
- Occludin
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Sujet
- This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
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Poids moléculaire
- 59 kDa
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NCBI Accession
- NP_002529
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Antigène
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