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PIM1 Protein (Myc-DYKDDDDK Tag)

Cette protéine Recombinant PIM1 est exprimée dans HEK-293 Cells.
N° du produit ABIN2728984

Aperçu rapide pour PIM1 Protein (Myc-DYKDDDDK Tag) (ABIN2728984)

Antigène

Voir toutes PIM1 Protéines
PIM1 (Pim-1 Oncogene (PIM1))

Type de proteíne

Recombinant

Origine

  • 7
  • 3
  • 1
  • 1
  • 1
Humain

Source

  • 8
  • 3
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Pureté

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification/Conjugué

    Cette PIM1 protéine est marqué à la Myc-DYKDDDDK Tag.

    Attributs du produit

    • Recombinant human PIM1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Indications d'application

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Commentaires

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Stock

    -80 °C

    Stockage commentaire

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène

    PIM1 (Pim-1 Oncogene (PIM1))

    Autre désignation

    Pim1

    Sujet

    The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011].

    Poids moléculaire

    35.5 kDa

    NCBI Accession

    NP_002639

    Pathways

    Glycosaminoglycan Metabolic Process
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