Ribonuclease H1 Protein (RNASEH1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2730997

Cette protéine Recombinant Ribonuclease H1 est exprimée dans HEK-293 Cells.

Aperçu rapide pour Ribonuclease H1 Protein (RNASEH1) (Myc-DYKDDDDK Tag) (ABIN2730997)

Antigène: Ribonuclease H1 (RNASEH1)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Purification/Conjugué: Cette Ribonuclease H1 protéine est marqué à la Myc-DYKDDDDK Tag.

Attributs du produit:

• Recombinant human RNASEH1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Ribonuclease H1 (RNASEH1)

Autre désignation: Rnaseh1

Sujet: This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes two of them are at different locations of chromosome 17 and one of them is on chromosome 1q32.2.

Poids moléculaire: 31.9 kDa

NCBI Accession: NP_002927