Seladin 1 Protein (Myc-DYKDDDDK Tag)
Aperçu rapide pour Seladin 1 Protein (Myc-DYKDDDDK Tag) (ABIN2731608)
Antigène
Voir toutes Seladin 1 (DHCR24) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette Seladin 1 protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human Seladin-1 / DHCR24 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
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Autre désignation
- Seladin-1,dhcr24
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Sujet
- This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
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Poids moléculaire
- 57.6 kDa
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NCBI Accession
- NP_055577
Antigène
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