TIMELESS Protein (Myc-DYKDDDDK Tag)
Aperçu rapide pour TIMELESS Protein (Myc-DYKDDDDK Tag) (ABIN2733738)
Antigène
Type de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette TIMELESS protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human Timeless (Tim) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TIMELESS (Timeless Homolog (TIMELESS))
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Autre désignation
- Timeless (Tim)
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Sujet
- The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.
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Poids moléculaire
- 138.5 kDa
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NCBI Accession
- NP_003911
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Pathways
- Protein targeting to Nucleus, Photoperiodism
Antigène
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