TIMM8A/DDP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Aperçu rapide pour TIMM8A/DDP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2733742)
Antigène
Voir toutes TIMM8A/DDP (TIMM8A) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- Transcript Variant 1
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Purification/Conjugué
- Cette TIMM8A/DDP protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human TIMM8A (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
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Autre désignation
- Timm8a
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Sujet
- This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2009]
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Poids moléculaire
- 10.8 kDa
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NCBI Accession
- NP_004076
Antigène
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