Thymic Stromal Lymphopoietin Protein (TSLP) (Transcript Variant 1)
Aperçu rapide pour Thymic Stromal Lymphopoietin Protein (TSLP) (Transcript Variant 1) (ABIN2734446)
Antigène
Voir toutes Thymic Stromal Lymphopoietin (TSLP) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- Transcript Variant 1
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Attributs du produit
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- Recombinant human TSLP (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
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niveau d'endotoxine
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Restrictions
- For Research Use only
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Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
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Conseil sur la manipulation
- Resuspend the protein in the desired concentration in proper buffer
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Thymic Stromal Lymphopoietin (TSLP)
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Autre désignation
- Tslp
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Sujet
- This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
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Poids moléculaire
- 15 kDa
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NCBI Accession
- NP_149024
Antigène
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