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Thymic Stromal Lymphopoietin Protein (TSLP) (Transcript Variant 1)

Cette protéine Recombinant Thymic Stromal Lymphopoietin est produite dans Escherichia coli (E. coli).
N° du produit ABIN2734446

Aperçu rapide pour Thymic Stromal Lymphopoietin Protein (TSLP) (Transcript Variant 1) (ABIN2734446)

Antigène

Voir toutes Thymic Stromal Lymphopoietin (TSLP) Protéines
Thymic Stromal Lymphopoietin (TSLP)

Type de proteíne

Recombinant

Origine

  • 22
  • 11
  • 5
  • 3
Humain

Source

  • 17
  • 16
  • 4
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Application

Antibody Production (AbP), Standard (STD)

Pureté

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • Attributs du protein

    Transcript Variant 1

    Attributs du produit

    • Recombinant human TSLP (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone

    niveau d'endotoxine

    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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  • Indications d'application

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Restrictions

    For Research Use only
  • Buffer

    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

    Conseil sur la manipulation

    Resuspend the protein in the desired concentration in proper buffer

    Stock

    -80 °C

    Stockage commentaire

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène

    Thymic Stromal Lymphopoietin (TSLP)

    Autre désignation

    Tslp

    Sujet

    This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.

    Poids moléculaire

    15 kDa

    NCBI Accession

    NP_149024
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