UNC45B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2735016

Cette protéine Recombinant UNC45B est produite dans HEK-293 Cells.

Aperçu rapide pour UNC45B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2735016)

Antigène: UNC45B (Unc-45 Homolog B (UNC45B))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Attributs du protein: Transcript Variant 1

Purification/Conjugué: Cette UNC45B protéine est marqué à la Myc-DYKDDDDK Tag.

Attributs du produit:

• Recombinant human UNC45B (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: UNC45B (Unc-45 Homolog B (UNC45B))

Autre désignation: Unc45b

Sujet: This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 103.6 kDa

NCBI Accession: NP_775259