Nerve Growth Factor Protein (NGF) (AA 122-241)

N° du produit ABIN2830300

Cette protéine Recombinant Nerve Growth Factor est produite dans Mammalian Cells.

Aperçu rapide pour Nerve Growth Factor Protein (NGF) (AA 122-241) (ABIN2830300)

Antigène: Nerve Growth Factor (NGF)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Mammalian Cells

Application: Functional Studies (Func)

Pureté: >90 % as determined by SDS-PAGE.

Détail du produit

Attributs du protein: AA 122-241

Séquence: Ser122-Ala241, Accession # CAA36832

Attributs du produit: Biological Activity: The ED50, as determined by a cell proliferation assay using human TF-1 cells, is less than 2 ng/mL.

Stérilité: 0.2 μm filtered

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.2 % acetic acid

Stock: -20 °C

Détail du antigène

Antigène: Nerve Growth Factor (NGF)

Autre désignation: NGF

Sujet: Relevance: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177). {ECO:0000269|PubMed:20164177}.
Synonyms: Beta-NGF,

Poids moléculaire: 13.5 kDa

UniProt: P01138

Pathways: Regulation of Cell Size