Vitamin D-Binding Protein Protein (GC) (AA 17-474) (His tag)

N° du produit ABIN4370809

Protéine Recombinant Vitamin D-Binding Protein exprimée dans Human Cells.

Aperçu rapide pour Vitamin D-Binding Protein Protein (GC) (AA 17-474) (His tag) (ABIN4370809)

Antigène: Vitamin D-Binding Protein (GC)

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 17-474

Purification/Conjugué: Cette Vitamin D-Binding Protein protéine est marqué à la His tag.

Fonction: Recombinant Human Vitamin D-Binding Protein/VDB/Gc-globulin (C-6His)

Séquence: LERGRDYEKN KVCKEFSHLG KEDFTSLSLV LYSRKFPSGT FEQVSQLVKE VVSLTEACCA EGADPDCYDT RTSALSAKSC ESNSPFPVHP GTAECCTKEG LERKLCMAAL KHQPQEFPTY VEPTNDEICE AFRKDPKEYA NQFMWEYSTN YGQAPLSLLV SYTKSYLSMV GSCCTSASPT VCFLKERLQL KHLSLLTTLS NRVCSQYAAY GEKKSRLSNL IKLAQKVPTA DLEDVLPLAE DITNILSKCC ESASEDCMAK ELPEHTVKLC DNLSTKNSKF EDCCQEKTAM DVFVCTYFMP AAQLPELPDV ELPTNKDVCD PGNTKVMDKY TFELSRRTHL PEVFLSKVLE PTLKSLGECC DVEDSTTCFN AKGPLLKKEL SSFIDKGQEL CADYSENTFT EYKKKLAERL KAKLPDATPT ELAKLVNKRS DFASNCCSIN SPPLYCDSEI DAELKNILVD HHHHHH

Attributs du produit: Recombinant Human Vitamin D-Binding Protein/GC is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu17-Leu474) of Human GC fused with a polyhistidine tag at the C-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: Vitamin D-Binding Protein (GC)

Autre désignation: Vitamin D-Binding Protein

Sub Type: Fusionprotein

Sujet: Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
Alternative Names: Vitamin D-Binding Protein, DBP, VDB, Gc-Globulin, Group-Specific Component, GC

Poids moléculaire: 52.3 kDa

UniProt: P02774

Pathways: Metabolism of Steroid Hormones and Vitamin D, Monocarboxylic Acid Catabolic Process