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VEGF110 (AA 27-136) (Active) Protéine

Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
N° du produit ABIN4948990
  • Antigène
    VEGF110
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 27-136
    Origine
    Humain
    Source
    • 1
    HEK-293 Cells
    Application
    Functional Studies (Func)
    Marque
    ActiveMax®
    Séquence
    AA 27-136
    Attributs du produit
    This protein carries no "tag". The protein has a calculated MW of 12.6 kDa. As a result of glycosylation, the protein migrates as 18-20 kDa under reducing (R) condition, and 40-45 kDa (homodimer) under non-reducing (NR) condition (SDS-PAGE).
    Pureté
    >95 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
  • Antigène
    VEGF110
    Sujet
    Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, and is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. Alternatively spliced isoforms of 110,121,145,165,183,189 and 206 amino acids in length are expressed in humans.
    Poids moléculaire
    12.7 kDa
    NCBI Accession
    NP_001165097
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