ANGPTL4 Protein (DYKDDDDK-His Tag)
Aperçu rapide pour ANGPTL4 Protein (DYKDDDDK-His Tag) (ABIN5505553)
Antigène
Voir toutes ANGPTL4 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette ANGPTL4 protéine est marqué à la DYKDDDDK-His Tag.
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Attributs du produit
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- Recombinant human Purified recombinant protein of human angiopoietin-like 4 (ANGPTL4), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 μg (C-term DDK/His tag, transcript variant 1) protein expressed in Human HEK293 cells.
- Produced with end-sequenced ORF clone
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Purification
- Purified
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 1 x PBS, pH 7.4, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
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Autre désignation
- angiopoietin-like 4
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Sujet
- This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
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Poids moléculaire
- 18 kDa
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NCBI Accession
- NP_647475
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Antigène
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