CD276 Protein (CD276) (DYKDDDDK-His Tag)

N° du produit ABIN5505582

Cette protéine Recombinant CD276 est produite dans HEK-293 Cells.

Aperçu rapide pour CD276 Protein (CD276) (DYKDDDDK-His Tag) (ABIN5505582)

Antigène: CD276

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Purification/Conjugué: Cette CD276 protéine est marqué à la DYKDDDDK-His Tag.

Attributs du produit:

• Recombinant human Purified recombinant protein of human CD276 Molecule (CD276), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 μg (C-term DDK/His tag, transcript variant 1) protein expressed in Human HEK293 cells.
• Produced with end-sequenced ORF clone

Purification: Purified

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 1 x PBS, pH 7.4, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CD276

Autre désignation: CD276 molecule

Sujet: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 49 kDa

NCBI Accession: NP_001019907

Pathways: Cancer Immune Checkpoints