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INHBB Protéine

Cette protéine Recombinant INHBB est produite dans Hi-5 Cells.
N° du produit ABIN5505690

Aperçu rapide pour INHBB Protéine (ABIN5505690)

Antigène

Voir toutes INHBB Protéines
INHBB (Inhibin, beta B (INHBB))

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
Humain

Source

  • 11
  • 4
  • 2
Hi-5 Cells

Application

Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)

Pureté

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • Specificité

    Optimal preservation of protein structure, post-translational modifications and functions.

    Attributs du produit

    • Recombinant human Inhibin beta B chain (INHBB) protein expressed in Hi-5 insect cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.

    niveau d'endotoxine

    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

    Biological Activity Comment

    ED50 was determined by its ability to inhibit the proliferation of murine MPC-11 cells is less than or equal to 2.0 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg.
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  • Indications d'application

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays

    Restrictions

    For Research Use only
  • Buffer

    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

    Conseil sur la manipulation

    Resuspend the protein in the desired concentration in proper buffer

    Stock

    -80 °C

    Stockage commentaire

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène

    INHBB (Inhibin, beta B (INHBB))

    Autre désignation

    Inhibin beta B chain (INHBB)

    Sujet

    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. [UniProtKB/Swiss-Prot Function]

    Poids moléculaire

    25.6 kDa

    NCBI Accession

    NP_002184

    Pathways

    Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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