INHBB Protéine
Aperçu rapide pour INHBB Protéine (ABIN5505690)
Antigène
Voir toutes INHBB ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Specificité
- Optimal preservation of protein structure, post-translational modifications and functions.
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Attributs du produit
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- Recombinant human Inhibin beta B chain (INHBB) protein expressed in Hi-5 insect cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
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niveau d'endotoxine
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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Biological Activity Comment
- ED50 was determined by its ability to inhibit the proliferation of murine MPC-11 cells is less than or equal to 2.0 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg.
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays -
Restrictions
- For Research Use only
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Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
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Conseil sur la manipulation
- Resuspend the protein in the desired concentration in proper buffer
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- INHBB (Inhibin, beta B (INHBB))
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Autre désignation
- Inhibin beta B chain (INHBB)
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Sujet
- Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. [UniProtKB/Swiss-Prot Function]
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Poids moléculaire
- 25.6 kDa
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NCBI Accession
- NP_002184
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Pathways
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
Antigène
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