CD28H (partial) protein (Fc Tag)
Aperçu rapide pour CD28H (partial) protein (Fc Tag) (ABIN5608281)
Antigène
Type de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- partial
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Purification/Conjugué
- Fc Tag
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Séquence
- Leu 23 - Gly 150
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niveau d'endotoxine
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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Indications d'application
- This recombinant protein can be used for WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- CD28H
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Sujet
- CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
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Poids moléculaire
- 40.6 kDa
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ID gène
- 126259
Antigène
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