PD-L1 Protein (partial) (Fc Tag)

N° du produit ABIN5608343

Protéine Recombinant PD-L1 exprimée dans HEK-293 Cells.

Aperçu rapide pour PD-L1 Protein (partial) (Fc Tag) (ABIN5608343)

Antigène: PD-L1 (CD274 (PD-L1))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Application: Western Blotting (WB)

Pureté: >95 % as determined by SDS-PAGE.

Détail du produit

Attributs du protein: partial

Purification/Conjugué: Cette PD-L1 protéine est marqué à la Fc Tag.

Séquence: Phe 19 - Thr 238

niveau d'endotoxine: Endotoxin level is less than 0.1 EU per ug by the LAL method.

Information d'application

Indications d'application: This recombinant protein can be used for WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C,-80 °C

Stockage commentaire: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Détail du antigène

Antigène: PD-L1 (CD274 (PD-L1))

Autre désignation: PD-L1

Sujet: Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

Poids moléculaire: 51.8 kDa

ID gène: 60533

UniProt: Q9EP73

Pathways: Cancer Immune Checkpoints