CD276 Protein (CD276) (partial) (His tag)

N° du produit ABIN5608364

Protéine Recombinant CD276 exprimée dans HEK-293 Cells.

Aperçu rapide pour CD276 Protein (CD276) (partial) (His tag) (ABIN5608364)

Antigène: CD276

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Application: Western Blotting (WB)

Pureté: >95 % as determined by SDS-PAGE.

Détail du produit

Attributs du protein: partial

Purification/Conjugué: Cette CD276 protéine est marqué à la His tag.

Séquence: Val 29 - Phe 244

niveau d'endotoxine: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Information d'application

Indications d'application: This recombinant protein can be used for WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C,-80 °C

Stockage commentaire: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Détail du antigène

Antigène: CD276

Autre désignation: B7-H3

Sujet: B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.

Poids moléculaire: 25.4 kDa

ID gène: 102657

NCBI Accession: NP_598744

UniProt: Q8VE98

Pathways: Cancer Immune Checkpoints