Glyco (AA 20-459) protein (His-SUMO Tag)
Aperçu rapide pour Glyco (AA 20-459) protein (His-SUMO Tag) (ABIN5711133)
Antigène
Type de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 20-459
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Purification/Conjugué
- His-SUMO Tag
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Séquence
- KFPIYTILDK LGPWSPIDIH HLSCPNNLVV EDEGCTNLSG FSYMELKVGY ILAIKMNGFT CTGVVTEAET YTNFVGYVTT TFKRKHFRPT PDACRAAYNW KMAGDPRYEE SLHNPYPDYR WLRTVKTTKE SLVIISPSVA DLDPYDRSLH SRVFPSGKCS GVAVSSTYCS TNHDYTIWMP ENPRLGMSCD IFTNSRGKRA SKGSETCGFV DERGLYKSLK GACKLKLCGV LGLRLMDGTW VAMQTSNETK WCPPDQLVNL HDFRSDEIEH LVVEELVRKR EECLDALESI MTTKSVSFRR LSHLRKLVPG FGKAYTIFNK TLMEADAHYK SVRTWNEILP SKGCLRVGGR CHPHVNGVFF NGIILGPDGN VLIPEMQSSL LQQHMELLES SVIPLVHPLA DPSTVFKDGD EAEDFVEVHL PDVHNQVSGV DLGLPNWGKY
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Purification
- SDS-PAGE
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Stock
- -80 °C,4 °C,-20 °C
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Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Glyco
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Classe de substances
- Viral Protein
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Sujet
- Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell mbrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
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Poids moléculaire
- 65.46 kDa
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UniProt
- P03524
Antigène
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