RAB5 Protéine

N° du produit ABIN5776883

Cette protéine Recombinant RAB5 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour RAB5 Protéine (ABIN5776883)

Antigène: RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Rat

Source: Escherichia coli (E. coli)

Pureté: > 90 % (SDS-PAGE)

Détail du produit

Fonction: Rab5A, Ras-associated, small GTP-binding protein, rat, recombinant, E. coli

Biological Activity Comment: 100 pmol of protein can bind > 80 pmol of GDP.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in 25 mM HEPES pH 7.240 mM NaCl2 mM MgCl210 μM GDP and 3 mM TCEP

Conseil sur la manipulation: Please centrifuge briefly before opening (volume ≤2 ml).,avoid freeze/thaw cycles

Stock: -80 °C

Stockage commentaire: store at -80 °C avoid freeze/thaw cycles

Date de péremption: 12 months

Détail du antigène

Antigène: RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

Autre désignation: Rab5A

Sujet: Rab5A is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The small Rab5A GTPase is localized to plasma membrane, clathrin coated vesicles, caveosomes and early endosomes. Rab5 is a key regulator of the early endocytic pathway and plays a role in early endosome fusion and caveolar vesicle targeting to early endosomes. Furtermore it is also implicated in EGF receptor activation and apoptotic cell engulfment.

Poids moléculaire: 24 kDa

NCBI Accession: NP_073183

Pathways: Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity