RCC1 Protéine
Aperçu rapide pour RCC1 Protéine (ABIN5776891)
Antigène
Voir toutes RCC1 ProtéinesType de proteíne
Origine
Source
Pureté
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Fonction
- RCC1 (RanGEF), Regulator of Chromosome Condensation, Ran Guanine Exchange Factor, human, recombinant, E. coli
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Regulator of Chromosome Condensation 1 (RCC1) (AA 1-421) protein (GST tag)
RCC1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, AP, AA, WB
Regulator of Chromosome Condensation 1 (RCC1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)RCC1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied in 20 mM HEPES pH 7.650 mM NaCl and 2 mM DTE
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Conseil sur la manipulation
- Please centrifuge briefly before opening (volume ≤2 ml).,avoid freeze/thaw cycles
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Stock
- -80 °C
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Stockage commentaire
- store at -80 °C avoid freeze/thaw cycles
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Date de péremption
- 12 months
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- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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Autre désignation
- RCC1 (RanGEF)
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Sujet
- RCC1 (Regulator of Chromosome Condensation, a β propeller chromatin-bound protein) catalyzes guanine nucleotide exchange of the Ras-related nuclear protein Ran. RCC1 is the guanine nucleotide exchange factor (GEF) for Ran which induces exchange between the bound GDP and cellular GTP. Genetic studies have suggested that RCC1 may be involved in sensing the replication state of DNA and controlling the activation of Cdc2/cyclin B protein kinase through Ran.
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Poids moléculaire
- 44.97 kDa (421 amino acids)
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Pathways
- Chromatin Binding, Protein targeting to Nucleus
Antigène
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