Peroxiredoxin 5 Protein (PRDX5) (AA 53-214)
Aperçu rapide pour Peroxiredoxin 5 Protein (PRDX5) (AA 53-214) (ABIN7281359)
Antigène
Voir toutes Peroxiredoxin 5 (PRDX5) ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- AA 53-214
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Séquence
- MAPIKVGDAI PAVEVFEGEP GNKVNLAELF KGKKGVLFGV PGAFTPGCSK THLPGFVEQA EALKAKGVQV VACLSVNDAF VTGEWGRAHK AEGKVRLLAD PTGAFGKETD LLLDDSLVSI FGNRRLKRFS MVVQDGIVKA LNVEPDGTGL TCSLAPNIIS QL
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niveau d'endotoxine
- < 1.0 EU per 1ug of protein (determined by LAL method)
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Biological Activity Comment
- Specific activity is >9,000 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for 1minute.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Bioactivity Validated
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. In 20 mM HEPES ( pH 7.4)
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Peroxiredoxin 5 (PRDX5)
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Autre désignation
- PRDX5
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Sujet
- Peroxiredoxin 5, also known as PRDX5, is a member of the peroxiredoxin family of antioxidant enzymes, which reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. This protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. It has been reported that PRDX5 is involved in intracellular redox signaling. Recombinant human PRDX5, was expressed in E.coli and purified by using conventional chromatography techniques.
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Poids moléculaire
- 17kDa (162aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_036226
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UniProt
- P30044
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Pathways
- Cell RedoxHomeostasis
Antigène
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