TXN Protein (AA 2-105, full length) (GST tag)

N° du produit ABIN7479607

Cette protéine Recombinant TXN est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour TXN Protein (AA 2-105, full length) (GST tag) (ABIN7479607)

Antigène: TXN (Thioredoxin (TXN))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS), Western Blotting (WB), ELISA

Pureté: 95 %

Détail du produit

Attributs du protein: AA 2-105, full length

Purification/Conjugué: Cette TXN protéine est marqué à la GST tag.

Séquence: VKQIESKTAF QEALDAAGDK LVVVDFSATW CGPCKMIKPF FHSLSEKYSN VIFLEVDVDD CQDVASECEV KCMPTFQFFK KGQKVGEFSG ANKEKLEATI NELV

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS buffer, 20mM GSH

Stock: 4 °C

Détail du antigène

Antigène: TXN (Thioredoxin (TXN))

Autre désignation: Thioredoxin

Sujet: Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. Ref.16 Ref.18 Ref.19 Ref.21 Ref.24 ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55). Synonyms: Short name=Trx Alternative name(s): ATL-derived factor Short name=ADF Surface-associated sulphydryl protein Short name=SASP.

Poids moléculaire: 39 kD

NCBI Accession: NM_003329

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis