Liver Arginase Protein (active Mutant)
Aperçu rapide pour Liver Arginase Protein (active Mutant) (ABIN6253489)
Antigène
Voir toutes Liver Arginase (ARG1) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- active Mutant
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Fonction
- Arginase I (human) (rec.) (highly active)
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Specificité
- Full length human arginase I.
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Réactivité croisée
- Humain
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Attributs du produit
- Full length human arginase I.
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Biological Activity Comment
- 1.6 ±0.2U/μg protein. One unit is defined as the amount of enzyme that converts 1μmol of L-arginine to L-ornithine and urea per min. at 37°C, pH 9.5 (according to protocol from R.T. Schimke, et al., J. Biol. Chem. 238, 1012 (1963)).
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Arginase, Liver (ARG1) (AA 1-322) protein (His tag)
custom-made ARG1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Arginase, Liver (ARG1) (AA 1-323) protein (His tag)custom-made ARG1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Arginase, Liver (ARG1) (AA 1-322) protein (His-IF2DI Tag)ARG1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Arginase, Liver (ARG1) (AA 1-322) protein (GST tag)ARG1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP
Arginase, Liver (ARG1) protein (MYC tag,His tag)ARG1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Arginase, Liver (ARG1) (Active) protein (Myc-DYKDDDDK Tag)ARG1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 μg/μL
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Buffer
- In 10 mM TRIS-HCl, pH 7.5, containing 1 mM beta-mercaptoethanol, 1 mM MnCl2 and 50 % glycerol.
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Conseil sur la manipulation
- Avoid freeze/thaw cycles.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
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Short Term Storage: -20°C
Long Term Storage: -80°C
Use & Stability: Stable for at least 1 year after receipt when stored at -80°C.
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Date de péremption
- 12 months
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- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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Autre désignation
- Arginase I
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Sujet
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EC 3.5.3.1, ARG1, Arginase 1, Type I Arginase, Liver-type Arginase, L-Arginase
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Arginase is involved in the nitric oxide (NO) pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general.
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Poids moléculaire
- 34.7kDa
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UniProt
- P05089
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Antigène
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