TARDBP Protein (AA 1-414)
Aperçu rapide pour TARDBP Protein (AA 1-414) (ABIN7281189)
Antigène
Voir toutes TARDBP ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 1-414
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Séquence
- MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA EPKHNSNRQL ERSGRFGGNP GGFGNQGGFG NSRGGGAGLG NNQGSNMGGG MNFGAFSINP AMMAAAQAAL QSSWGMMGML ASQQNQSGPS GNNQNQGNMQ REPNQAFGSG NNSYSGSNSG AAIGWGSASN AGSGSGFNGG FGSSMDSKSS GWGM
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TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (His tag)
custom-made TARDBP Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (His tag)custom-made TARDBP Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TAR DNA Binding Protein (TARDBP) protein (Myc-DYKDDDDK Tag)TARDBP Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
TAR DNA Binding Protein (TARDBP) (AA 8-192) protein (His-IF2DI Tag)TARDBP Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
TAR DNA Binding Protein (TARDBP) (AA 1-260) protein (His tag)TARDBP Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (GST tag)TARDBP Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
TAR DNA Binding Protein (TARDBP) (AA 1-260) protein (GST tag)TARDBP Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (His tag)TARDBP Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- Liquid. In 20 mM Tris-HCl( pH 8.0) containing 0.1M NaCl, 1 mM DTT, 1 mM EDTA, 10 % glycerol
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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Autre désignation
- TDP-43/TARDBP
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Sujet
- TARDBP, as known as TAR DNA binding protein 43, was originally identified as a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. It has also been identified in individuals diagnosed with chronic traumatic encephalopathy, a condition that often mimics ALS and that has been associated with athletes who have experienced multiple concussions and other types of head injury. It has been shown to bind both DNA and RNA and have multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation. Recombinant human TARDBP protein was expressed in E. coli and purified by using conventional chromatography.
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Poids moléculaire
- 44.7 kDa (414aa)
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NCBI Accession
- NP_031401
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UniProt
- Q13148
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Antigène
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