FH Protein (AA 44-510)

N° du produit ABIN666730

Protéine Recombinant FH exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour FH Protein (AA 44-510) (ABIN666730)

Antigène: FH (Fumarate Hydratase (FH))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 95 % by SDS - PAGE

Détail du produit

Attributs du protein: AA 44-510

Attributs du produit: Fumarase, 44-510aa, Human, Recombinant, E.coli

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0)

Stock: 4 °C

Détail du antigène

Antigène: FH (Fumarate Hydratase (FH))

Autre désignation: Fumarase

Sujet: Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor. Recombinant Fumarase was expressed in E.coli and was purified by conventional chromatography techniques. Synonyms: FH, HLRCC, LRCC, MCL, MCUL1 , Fumarate hydratase Fumarase, Fumarate hydratase mitochondrial, MCUL 1, Multiple hereditary cutaneous leiomyomata. NCBI no.: NP_000134

Poids moléculaire: 50.2kDa (467aa), confirmed by MALDI-TOF.