Nanog Protein (AA 1-305)

N° du produit ABIN667504

Protéine Nanog exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Nanog Protein (AA 1-305) (ABIN667504)

Antigène: Nanog (NANOG) (Nanog Homeobox (NANOG))

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 90 % by SDS - PAGE

Détail du produit

Attributs du protein: AA 1-305

Attributs du produit: NANOG, 1-305aa, Human, E.coli

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 5% glycerol

Stock: 4 °C

Détail du antigène

Antigène: Nanog (NANOG) (Nanog Homeobox (NANOG))

Autre désignation: NANOG

Sujet: Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Synonyms: Nanog homeobox, Homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48. NCBI no.: NP_079141

Poids moléculaire: 34.6 kDa (305aa)

Pathways: Stem Cell Maintenance