RCAN1 Protein (AA 1-117)

N° du produit ABIN667702

Protéine Recombinant RCAN1 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour RCAN1 Protein (AA 1-117) (ABIN667702)

Antigène: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 90 %

Détail du produit

Attributs du protein: AA 1-117

Séquence: MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS

Attributs du produit: DSCR1 isoform b, 1-117aa , Human, Recombinant, E.coli

Purification: > 90% by SDS-PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 7.5) containing 0.1M NaCl, 1 mM DTT, 10 % Glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Autre désignation: Calcipressin-1/DSCR1

Sujet: The Down's syndrome candidate region 1 (DSCR1) protein, encoded by a gene located in the human chromosome 21, interacts with calcineurin and is overexpressed in Down's syndrome patients. DSCR1 Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, possibly affecting central nervous system development. DSCR isoform b is shorter at the N-terminus compared to isoform a. Recombinant human DSCR1 was expressed in E. coli and purified by using conventional chromatography techniques.

Poids moléculaire: 13.2 kDa (117aa) confirmed by MALDI-TOF

NCBI Accession: NP_981962

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development