Peroxiredoxin 2 Protein (PRDX2) (AA 1-198)
Aperçu rapide pour Peroxiredoxin 2 Protein (PRDX2) (AA 1-198) (ABIN667730)
Antigène
Voir toutes Peroxiredoxin 2 (PRDX2) ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- AA 1-198
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Séquence
- MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN
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Attributs du produit
- Peroxiredoxin 2, 1-198 aa, Human, Recombinant, E.coli
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Purification
- > 90% by SDS-PAGE
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niveau d'endotoxine
- < 1 EU per 1ug of protein (determined by LAL method)
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Biological Activity Comment
- Specific activity is >2,000pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Peroxiredoxin 2 (PRDX2)
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Autre désignation
- Peroxiredoxin 2/PRDX2
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Sujet
- Peroxiredoxin 2, also known as PRDX2, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Peroxiredoxin 2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. If Peroxiredoxin 2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant human Peroxiredoxin 2 protein was expressed in E. coli and purified by using conventional chromatography.
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Poids moléculaire
- 21.8 kDa (198aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_005800
Antigène
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