Human Adenovirus type 3 (HAdV-3) Protéine

N° du produit ABIN6941928

Protéine Recombinant Human Adenovirus type 3 exprimée dans HEK-293 Cells.

Aperçu rapide pour Human Adenovirus type 3 (HAdV-3) Protéine (ABIN6941928)

Antigène: Human Adenovirus type 3 (HAdV-3)

Type de proteíne: Recombinant

Origine: Adenovirus

Source: HEK-293 Cells

Pureté: Purified virus

Détail du produit

Fonction: Wild type Adenovirus type 3. Concentrated and purified virus particles from a double CsCl gradient purification with DNase treatment and dialysis. Safety category BSL2.

Attributs du produit: Adenovirus Type 3 Particles, Wild-type
Human adenovirus type 3 particles (wild-type) produced in HEK293 cells and purified by CsCl gradient.

Purification: Human adenovirus type 3 particles (wild-type) produced in HEK293 cells and purified by CsCl gradient.

Information d'application

Indications d'application: 2.53x10^12 particles per mL (BCA assay)

Commentaires:

This product is a concentrated source of highly-purified human Adenovirus type 3 particles (wild-type) from a lysate of optimally-infected 293 cells. Following double CsCl gradient purification with DNase treatment and dialysis, this Ad3 preparation is of very high quality and minimal lot-to-lot variation.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 50 mM Hepes pH 7.8, 10 % Glycerol

Stock: -80 °C

Stockage commentaire: -80°C

Détail du antigène

Antigène: Human Adenovirus type 3 (HAdV-3)

Autre désignation: Adenovirus Type 3

Classe de substances: Virus

Sujet: Adenoviruses are medium-sized (80–100 nm), non-enveloped viruses. They have an icosahedral nucleocapsid containing a linear, double-stranded DNA genome of approximately 36 kb (Nermut, 1984). The viral genome is grouped into different transcriptional units, designated early (E1, E2, E3, E4), intermediate, and late. The E1 gene is essential for activation of other viral genes and for viral replication. Deletion of the E1 gene results in viruses that are replication incompetent in normal cells. However, replication-competent viral particles can be produced from E1-deleted viral vectors by providing the E1 gene in trans. The E3 gene is nonessential for either viral replication or infection (Flint, 1999).